What can significantly affect the stability of a crane during operation?

All of the options mentioned play a crucial role in the stability of a crane during its operation.

Weather conditions such as high winds, rain, or icy conditions can compromise the crane's ability to maintain stability. For instance, gusty winds can sway the crane or the load, making it difficult to control movements and increasing the risk of tipping over.

The type of crane used also significantly affects stability. Different cranes have varying designs, base widths, heights, and configurations that influence their operational stability. Some cranes are designed specifically for heavy loads in tight spaces while others may be suited for different types of lifting tasks, each affecting how they balance loads.

The load being lifted is a direct factor in determining stability. The weight, size, and center of gravity of the load can affect how the crane handles the lift. An uneven load or one that exceeds the crane's rated capacity can lead to loss of control and instability.

Considering the influence of all these factors, it is clear that they collectively determine how stable a crane will be during operation, thus making the answer that encompasses them all the most comprehensive and accurate.